John C. Reilly
| Year | Movie | Function | Role |
| 2012 | The Dictator | actor | |
| 2012 | Tim and Eric?s Billion Dollar Movie | actor | Taquito |
| 2011 | Carnage | actor | Michael |
| 2011 | We Need to Talk About Kevin | actor | Franklin |
| 2011 | Terri | actor | Mr. Fitzgerald |
| 2011 | Fight for Your Right Revisited | actor | Mike D (B-Boys 2) |
| 2011 | Cedar Rapids | actor | Dean Ziegler |
| 2010 | The Extra Man | actor | Gershon |
| 2010 | Cyrus | actor | John |
| 2009 | Scream Awards 2009 | actor | Himself |
| 2009 | Cirque du Freak: The Vampire's Assistant | actor | Larten Crepsley |
| 2009 | Zombieland | actor | Bathroomzombie (uncredited) |
| 2009 | 9 | actor | 5 (voice) |
| 2008 | The Promotion | actor | Richard Wehlner |
| 2008 | Step Brothers | writer | |
| 2008 | Step Brothers | actor | Dale Doback |
| 2007 | Walk Hard - The Dewey Cox Story | actor | Dewey Cox |
| 2007 | Year of the Dog | actor | Al |
| 2007 | The 79th Annual Academy Awards | actor | Himself - Co-Presenter: Best Makeup |
| 2006 | Tenacious D in The Pick of Destiny | actor | Sasquatch (uncredited) |
| 2006 | Talladega Nights: The Ballad of Ricky Bobby | actor | Cal Naughton Jr. |
| 2006 | A Prairie Home Companion | actor | Lefty |
| 2005 | Dark Water | actor | Mr. Murray |
| 2004 | The Aviator | actor | Noah Dietrich |
| 2004 | Criminal | actor | Richard Gaddis |
| 2003 | Anger Management | actor | Older Arnie Shankman (uncredited) |
| 2002 | Chicago | actor | Amos Hart |
| 2002 | The Hours | actor | Dan Brown |
| 2002 | Gangs of New York | actor | Happy Jack Mulraney |
| 2002 | The Good Girl | actor | Phil Last |
| 2001 | The Anniversary Party | actor | Mac Forsyth |
| 2000 | The Perfect Storm | actor | Dale 'Murph' Murphy |
| 1999 | Magnolia | actor | Officer Jim Kurring |
| 1999 | For Love of the Game | actor | Gus Sinski |
| 1999 | Never Been Kissed | actor | Gus |
| 1998 | The Thin Red Line | actor | Sgt. Storm |
| 1997 | Chicago Cab | actor | Steve |
| 1997 | Nightwatch | actor | Deputy Inspector Bill Davis (uncredited) |
| 1997 | Boogie Nights | actor | Reed Rothchild |
| 1996 | Boys | actor | Officer Kellogg Curry |
| 1996 | Hard Eight | actor | John |
| 1995 | Georgia | actor | Herman |
| 1995 | Dolores Claiborne | actor | Const. Frank Stamshaw |
| 1994 | The River Wild | actor | Terry |
| 1993 | What's Eating Gilbert Grape | actor | Tucker Van Dyke |
| 1992 | Hoffa | actor | Pete Connelly |
| 1992 | Out on a Limb | actor | Jim Jr. |
| 1991 | Shadows and Fog | actor | Cop at Police Station |
| 1990 | Days of Thunder | actor | Buck Bretherton |
| 1990 | State of Grace | actor | Stevie McGuire |
| 1989 | We're No Angels | actor | Young Monk |
| 1989 | Casualties of War | actor | Hatcher |